It's not out of the realm for him to no diff this crew. Akainu is a durability freak combined with some offensive tools that can OHKO a majority of the straw hats. Zoro and Sanji are physical fighters meaning they need to get close to deal any meaningful damage and if WB's face being blown in half is any indication, you'll realize how dangerous it is for them to even flirt with the idea. Akainu was taking some direct quake punches from a blood lusted Whitebeard and was able to retaliate with a magma punch. Really goes to show that taking the hit didn't really affect his ability to dish out damage.
G4 Luffy wasn't keeping up with a lower end commander. He needed Nami's assistance to extend the fight to 11 hours. Zoro isn't going to be doing much to him as well if we assume G4 is above him. A combination of Vista and Marco attacking Akainu irritated Akainu at best, coming out unscathed in that exchange.
One shot potential on irrelevant SH members and maybe 1-2 shots on the upper end while soaking all their damage with relative ease sounds like a no diff fight to me.